Generic
Diflu 50 is a fluconazole-based antifungal medication produced by Aristopharma Limited. Its active ingredient, fluconazole, works by targeting and disrupting fungal cell membranes, providing treatment for various fungal infections.

Description
Diflu 50 is an antifungal capsule containing 50 mg of fluconazole, effective for treating infections caused by fungi, such as Candida, affecting areas like the mouth, throat, vagina, and skin. It operates by stopping the growth and reproduction of fungi, making it widely used in antifungal therapy.

Benefits
The primary benefit of Diflu 50 is its effectiveness against a range of fungal infections, including candidiasis and other conditions caused by various Candida species. It is helpful in treating both superficial and systemic fungal infections, and, when appropriately prescribed, can prevent relapses of certain recurrent infections.

Ingredients
Diflu 50 consists of fluconazole as the active ingredient, with each capsule containing 50 mg of this antifungal agent. Inactive components include excipients that stabilize and protect the active ingredient.

Uses and Doses
Diflu 50 is indicated for treating fungal infections, with adult oral doses varying based on the type and severity of infection. For example, oropharyngeal candidiasis is typically treated with an initial 200 mg dose, followed by 100 mg daily, while systemic candidiasis may require up to 400 mg per day. Pediatric doses range from 3–12 mg/kg per day, adjusted according to age and weight. Consult your healthcare provider for specific dosing guidance.

Side Effects
Common side effects of Diflu 50 include nausea, headache, abdominal pain, rash, and vomiting. Rare but severe side effects can include liver toxicity, prolonged QT interval, and allergic reactions. Any unusual symptoms should be promptly reported to a healthcare professional.

How to Use
Diflu 50 should be taken orally, with or without food, as directed by your doctor. Swallow the capsule whole without crushing or breaking. For best results, take Diflu 50 at the same time each day to maintain a steady blood level.

Pregnancy & Lactation
Diflu 50 is generally not recommended during pregnancy, as studies suggest potential risk to the fetus, especially with high doses. Its use in pregnancy is restricted to cases where the benefit significantly outweighs potential risks. For breastfeeding mothers, Diflu 50 is considered relatively safe, but caution is advised as the drug may pass into breast milk.

Precautions and Warnings
Patients with liver or kidney impairment should use Diflu 50 cautiously, as these conditions may affect drug clearance. Those with known hypersensitivity to fluconazole or similar drugs should avoid this medication. It may cause dizziness, and patients should avoid driving if affected.

Safety Information
Diflu 50 should be taken under medical supervision, and patients should disclose any history of liver, kidney, or heart conditions before use. Alcohol consumption should be limited while taking this medication, as it may exacerbate side effects.

Indications
Diflu 50 is used for treating fungal infections such as cryptococcal meningitis, various forms of candidiasis, tinea infections, and other susceptible fungal infections.

Pharmacology
Fluconazole, the active ingredient in Diflu 50, belongs to the triazole class of antifungal agents. It inhibits fungal cytochrome P450 enzymes, crucial for synthesizing ergosterol, an essential component of the fungal cell membrane. This disruption of ergosterol production weakens and ultimately kills fungal cells.

Therapeutic Class
Diflu 50 is classified as a drug for subcutaneous and systemic mycoses.

Storage Conditions
Store Diflu 50 in a cool, dry place away from direct light and heat. Keep out of reach of children to prevent accidental ingestion.

3 FAQ

1. Can I take Diflu 50 with other medications? Always consult your doctor before combining Diflu 50 with other medications, especially anticoagulants, antihypertensives, or anticonvulsants.
2. Is Diflu 50 safe for long-term use? Prolonged use of Diflu 50 should be under medical supervision due to potential risks, including liver toxicity.
3. Can Diflu 50 be taken for nail infections? Yes, Diflu 50 is sometimes prescribed for fungal nail infections, though treatment duration may be prolonged.

Disclaimer
This summary does not replace medical advice. Consult your healthcare provider for personalized guidance based on your health status and current medications.

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