Generic Gliclazide

Description Diatrol is an oral hypoglycemic medication containing Gliclazide 80mg, formulated for the management of maturity-onset diabetes mellitus (NIDDM). Manufactured by Pacific Pharmaceuticals Ltd., this sulfonylurea drug promotes insulin secretion and improves blood glucose control in diabetic patients who require oral treatment.

Benefits: Diatrol helps regulate blood sugar levels in individuals with type 2 diabetes by stimulating insulin secretion from pancreatic beta cells. It also reduces hepatic glucose production, thereby preventing hyperglycemia. Compared to other sulfonylureas, it has a lower risk of causing sudden hypoglycemic episodes.

Ingredients Each tablet contains 80 mg of Gliclazide of Gliclazide as the active ingredient. Additional excipients may include fillers, binders, and stabilizing agents to ensure efficacy and stability.

Uses and Doses Diatrol is prescribed for patients with type 2 diabetes who require an oral hypoglycemic agent. The initial dosage is 40 to 80 mg daily, which may increase to 320 mg daily, divided into multiple doses. The medication should be taken before meals. The standard daily dose for modified-release Gliclazide 30 mg is 1 to 4 tablets, and for Gliclazide 60 mg, 1 to 2 tablets are taken as a single dose in the morning.

Side Effects Common side effects include nausea, headache, dizziness, and gastrointestinal disturbances. In some cases, hypoglycemia may occur, especially in individuals with concurrent illnesses such as hepatic or renal disease, starvation, or alcohol consumption. Skin reactions such as rash, pruritus, and erythema may also develop.

How to Use Diatrol should be taken orally before meals to maximize absorption and effectiveness. Patients should follow their physician’s instructions regarding the dosage and timing to avoid the risk of hypoglycemia.

Pregnancy & Lactation Gliclazide is not recommended for pregnant or breastfeeding women, as it may affect fetal development and lactation. Pregnant patients should consult their healthcare provider for alternative diabetes management options.

Precautions and Warnings Patients with hepatic impairment should take Diatrol with caution, as it may exacerbate liver dysfunction. Those undergoing surgery, experiencing infections, or suffering from diabetic ketoacidosis should avoid this medication. Diatrol should not be used in individuals with type 1 diabetes.

Safety Information: This medication should be used under the supervision of a physician. Patients should monitor their blood sugar levels regularly and avoid alcohol consumption, which may potentiate its hypoglycemic effect. In case of an overdose, medical attention is required immediately.

Indications Diatrol is indicated for the treatment of type 2 diabetes mellitus (NIDDM) in patients who require an oral hypoglycemic agent to control blood sugar levels.

Pharmacology Gliclazide belongs to the sulfonylurea class of drugs. It stimulates pancreatic beta cells to increase insulin secretion. It also enhances calcium transport across cell membranes, improving glycemic control. Additionally, it reduces hepatic glucose production, further aiding blood sugar regulation.

Therapeutic Class Sulfonylureas

Storage Conditions Store in a cool, dry place below 30°C, away from direct light and moisture. Keep out of the reach of children.

3 FAQ

1. Can Diatrol be used in type 1 diabetes?
   No, Diatrol is only indicated for type 2 diabetes and should not be used in individuals with type 1 diabetes.
2. What should I do if I miss a dose?
   If a dose is missed, take it as soon as possible unless it is almost time for the next dose. Do not double the dose.
3. Can I take Diatrol with other diabetes medications?
   Consult your doctor before combining Diatrol with other diabetes medications, as drug interactions may affect blood sugar control.

Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult a healthcare provider before starting any medication.

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