Denvar 400 Capsule contains Cefixime Trihydrate 400mg, a third-generation cephalosporin antibiotic for treating bacterial infections. Healthcare Pharmaceuticals Limited manufactures it, and it requires a prescription.

Description Denvar 400 Capsule is an oral antibiotic effective against many gram-positive and gram-negative bacteria. It is widely prescribed for infections of the urinary tract, respiratory tract, soft tissues, and gonorrhea. Its mechanism of action involves inhibiting bacterial cell wall synthesis, making it effective even against beta-lactamase-producing bacteria.

Benefits Denvar 400 Capsule provides broad-spectrum antibacterial coverage, making it an excellent option for treating urinary tract infections, respiratory infections, and sexually transmitted diseases. It offers convenient dosing and high patient compliance due to its once or twice-daily administration.

Ingredients Each capsule contains Cefixime Trihydrate 400mg, an extended-spectrum cephalosporin antibiotic known for its high stability against beta-lactamases.

Uses and Doses Denvar 400 is usually prescribed for 7 to 14 days, depending on the severity of the infection.

The recommended dose for adults and children over 12 years old is 200-400 mg daily, either in a single or two divided doses. For uncomplicated gonorrhea, a single 400 mg dose is recommended.

For children aged 6 months and older, the dosage is based on body weight:

• 6 months – 1 year: 75 mg daily
• 1–4 years: 100 mg daily
• 5–10 years: 200 mg daily
• 11–12 years: 300 mg daily

For typhoid fever, the dose is 10 mg/kg/day for 14 days.

Side Effects Denvar 400 is generally well tolerated. The most common side effects include diarrhea, nausea, vomiting, stomach pain, bloating, dizziness, and headache. Some patients may experience allergic reactions, such as rashes, itching, fever, and joint pain. These effects are usually mild and subside after stopping the medication.

How to Use Denvar 400 Capsules: Denvar 400 capsules should be taken with or without food. They should be swallowed whole with water and taken simultaneously each day to maintain steady antibiotic levels in the body.

Pregnancy & Lactation There are no well-controlled studies on using Cefixime in pregnant women, so it should be used only if necessary. It is not known if Cefixime is excreted in breast milk, so caution should be exercised while prescribing it to lactating mothers.

Precautions and Warnings Denvar 400 should be used cautiously in patients with a history of gastrointestinal diseases, especially colitis. Patients with severe renal impairment should receive a reduced dose. It may also interact with blood thinners, increasing the risk of bleeding.

Safety Information: Do not exceed the prescribed dose. If a dose is missed, take it as soon as possible. Avoid alcohol consumption during treatment, as it may enhance side effects. Seek medical attention if severe allergic reactions occur.

Denvar 400 is indicated for urinary tract infections, pharyngitis, tonsillitis, otitis media, bronchitis, gonorrhea, and other infections caused by susceptible bacteria.

Pharmacology Cefixime is a bactericidal antibiotic that inhibits bacterial cell wall synthesis, leading to cell death. It is well-absorbed orally and has a long half-life, allowing for convenient once or twice-daily dosing.

Therapeutic Class Denvar 400 belongs to the Third-Generation Cephalosporins class, known for its broad antibacterial activity.

Storage Conditions Store below 30ºC, protected from light and moisture. Keep out of reach of children.

3 FAQ

1. Can Denvar 400 be taken with food?
   • Yes, it can be taken with or without food, but taking it with food may reduce stomach discomfort.
2. Is Denvar 400 effective for viral infections?
   • No, it is only effective against bacterial infections, not viral illnesses like the flu or common cold.
3. What should I do if I miss a dose?
   • Take the missed dose as soon as you remember, but do not double the dose to make up for a missed one.

Disclaimer: This information is for educational purposes only and does not replace medical advice. Always consult a doctor before taking any medication.

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