Generic:
The active ingredient in Contine 200 is Theophylline, a bronchodilator often prescribed to treat symptoms of asthma, chronic obstructive pulmonary disease (COPD), and related bronchospasms.

Description:
Contine 200, a 200 mg tablet manufactured by Aristopharma Ltd., is a slow-release formulation of Theophylline that helps manage and prevent breathing problems such as asthma and bronchospasm by relaxing the smooth muscles in the respiratory tract and decreasing airway responsiveness to stimuli.

Benefits:
Contine 200 effectively reduces respiratory symptoms associated with asthma and COPD. Its primary actions include bronchodilation, increased pulmonary vasodilation, and stimulation of mucociliary clearance, making it effective for patients experiencing difficulty breathing and reducing symptoms linked to respiratory inflammation.

Ingredients:
Each Contine 200 tablet contains 200 mg of Theophylline, a xanthine derivative, which primarily functions as a bronchodilator.

Uses and Doses:
Contine 200 is used in managing asthma, COPD, and reversible bronchospasm. For adults, the dosage is individualized based on therapeutic response, typically starting at 300–400 mg/day. Pediatric doses vary with age, starting as low as 10 mg/kg/day in infants and increasing for older children. The tablet can be taken with or without food but should be taken at least one hour before or two hours after meals.

Side Effects:
Common side effects of Contine 200 include gastrointestinal discomfort, nausea, vomiting, diarrhea, headaches, insomnia, muscle twitching, and cardiovascular effects like palpitations and tachycardia. Rare but serious side effects may include severe hypotension, cardiac arrhythmias, and convulsions.

How to Use:
Contine 200 should be taken as directed by a physician, typically once or twice daily. The tablet should be swallowed whole and not crushed or chewed. Dosage adjustments may be required based on therapeutic response and tolerance levels.

Pregnancy & Lactation:
The safety of Theophylline in pregnancy is not well established, and it should only be used during pregnancy if clearly needed. Caution is advised during breastfeeding due to unknown excretion levels into breast milk.

Precautions and Warnings:
Special caution should be taken in patients with peptic ulcer, hyperthyroidism, epilepsy, cardiovascular diseases, and hepatic impairment. Regular monitoring of blood Theophylline levels may be required due to interactions and variations in drug clearance.

Safety Information:
Keep Contine 200 out of reach of children. Patients should avoid other xanthine derivatives during therapy and consult a healthcare provider about potential drug interactions.

Indications:
Contine 200 is indicated for asthma, COPD, and reversible bronchospasm management.

Pharmacology:
Theophylline works by inhibiting phosphodiesterase, leading to increased levels of cAMP. This results in bronchodilation, diuresis, central nervous system stimulation, and increased gastric acid secretion.

Therapeutic Class:
Theophylline is categorized as a bronchodilator and xanthine derivative.

Storage Conditions:
Store in a cool, dry place away from light and moisture.

3 FAQ:

1. What is Contine 200 used for?
   Contine 200 is prescribed to prevent and treat asthma and COPD-related symptoms by dilating the airways and enhancing breathing.
2. Can Contine 200 be used during pregnancy?
   Only if necessary, under a doctor’s supervision, as safety in pregnancy is not well established.
3. How should Contine 200 be stored?
   Store in a cool, dry place away from direct light and out of reach of children.

Disclaimer:
This information is provided for educational purposes only. Consult your healthcare provider before using Contine 200, especially if you are pregnant, nursing, or taking other medications.

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