Clovate 10 Ointment contains Clobetasol Propionate 0.05%, a high-potency topical corticosteroid manufactured by ACI Limited. It requires a prescription and is formulated to treat inflammatory skin conditions that do not adequately respond to less potent corticosteroids.

Description Clovate 10 Ointment is a topical corticosteroid that reduces inflammation, redness, and itching in severe dermatoses. It effectively treats psoriasis, recalcitrant dermatoses, lichen planus, and discoid lupus erythematosus. The ointment suppresses the immune response in the affected area, reducing symptoms.

Benefits Clovate 10 Ointment provides rapid relief from inflammation, itching, and swelling associated with severe skin conditions. It is effective for short-term management of chronic skin diseases, improving skin appearance, and reducing discomfort.

Ingredients Each gram of Clovate 10 Ointment contains Clobetasol Propionate 0.05%, which acts as an anti-inflammatory, anti-pruritic, and vasoconstrictor.

Uses and Doses Clovate 10 Ointment is for external use only. A thin layer should be applied twice daily to the affected area and gently rubbed. Treatment should not exceed two consecutive weeks; the maximum dose should not exceed 50g per week. In children, courses should be limited to five days and reviewed weekly.

Side Effects The most common side effects include burning, stinging, and itching at the application site. Prolonged use may lead to skin thinning, cracking, and systemic absorption, potentially causing Cushing’s syndrome and adrenal suppression.

How to Use: Clean and dry the affected area before applying a thin layer of Clovate 10 Ointment. Do not cover the area unless instructed by a doctor. Do not apply it to broken or infected skin.

Pregnancy & Lactation Use of Clovate 10 Ointment during pregnancy should be limited to cases where the benefit outweighs the risk. Topical corticosteroids may cause fetal development abnormalities in animals, but their relevance in humans is uncertain. It is unknown whether the drug is excreted in human breast milk, so caution is advised for nursing mothers.

Precautions and Warning: To prevent systemic absorption, Avoid using Clovate 10 Ointment on large areas of skin or for prolonged periods. If applied near the eyes, avoid contact to prevent cataracts and glaucoma. In psoriasis, use caution, l,y, as it may cause rebound relapses and local toxicity.

Safety Information Clovate 10 Ointment should not be used in children under 1 year old. Avoid prolonged sun exposure while using this medication. If irritation occurs, discontinue use and consult a doctor.

Indications Clovate 10 Ointment is indicated for treating psoriasis (excluding widespread plaque psoriasis), lichen planus, recalcitrant dermatoses, discoid lupus erythematosus, and other conditions that do not respond to less potent steroids.

Pharmacology Clobetasol Propionate is a super-high potency corticosteroid that inhibits inflammatory mediators and suppresses late-phase allergic reactions. It decreases mast cell density, chemotaxis, eosinophil activation, and cytokine production, reducing inflammation and immune response.

Therapeutic Class Clovate 10 Ointment belongs to the Topical Corticosteroids category, primarily used for treating inflammatory skin disorders.

Storage Conditions: Store below 30°C, away from direct heat and light. Keep out of reach of children.

3 FAQ

1. Can Clovate 10 Ointment be used for acne?
   • No, it is not recommended for acne or fungal infections.
2. How long does Clovate 10 take to work?
   • Improvement is usually seen within a few days, but the total duration of treatment should not exceed two weeks.
3. Can I use this ointment on my face?
   • Only if prescribed by a doctor. Prolonged use on the face can cause skin thinning and other adverse effects.

Disclaimer: This content is for informational purposes only and does not replace professional medical advice. Always consult a doctor before using any medication.

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