Generic:
Clovate N 15 Ointment is a potent topical medication containing Clobetasol Propionate, Neomycin Sulphate, and Nystatin, designed to treat various inflammatory and infective skin conditions.

Description:
Clovate N 15 Ointment combines the anti-inflammatory power of Clobetasol Propionate with the antibacterial action of Neomycin Sulphate and the antifungal properties of Nystatin. This makes it an effective treatment for complex skin conditions where inflammation, bacterial, and fungal infections coexist.

Benefits:

• Reduces severe inflammation and relieves itching.
• Combats bacterial infections on the skin.
• Treats fungal infections, providing a broad-spectrum treatment.
• Suitable for short-term use in resistant skin conditions.

Ingredients:

• Clobetasol Propionate 0.50mg
• Neomycin Sulphate 5mg
• Nystatin 100000IU

Uses and Doses:
Clovate N 15 Ointment is used for:

• Short courses in treating stubborn eczemas and neurodermatoses.
• Managing psoriasis, especially where bacterial or fungal infections are present.
• Treating other inflammatory skin conditions unresponsive to less potent steroids.

Dosage:

• Adults and children over 2 years: Apply sparingly to the affected area once or twice daily until improvement is observed. Do not use for more than 7 days without medical supervision. If longer treatment is required, reassess after 4 weeks.

Side Effects:
Possible side effects include:

• Skin thinning and stretch marks.
• Local skin atrophy.
• Increased risk of systemic absorption leading to hypercortisolism.
• Potential for pigmentation changes and hair growth in treated areas.

How to Use:
Apply a thin layer to the affected area 1-2 times daily. Avoid prolonged use and contact with the eyes. In cases of severe lesions, occlusive dressings can be used to enhance absorption under medical guidance.

Pregnancy & Lactation:

• Not recommended during pregnancy due to potential fetal toxicity.
• Safety in nursing mothers is not established; consult a healthcare provider before use.

Precautions and Warnings:

• Avoid long-term use to prevent adrenal suppression, especially in infants and children.
• Care should be taken when applying near the eyes.
• Monitor for signs of skin atrophy and systemic absorption.

Safety Information:

• Do not use it on viral skin infections like herpes or chickenpox.
• Not for use in rosacea, acne, or perioral dermatitis.
• Keep out of reach of children and store below 25°C.

Indications:
Clovate N 15 Ointment is indicated for:

• Psoriasis (excluding widespread plaque psoriasis).
• Recalcitrant eczemas and neurodermatoses.
• Inflammatory skin conditions with secondary infections.

Pharmacology:

• Clobetasol Propionate: A high-potency corticosteroid that reduces inflammation and itching.
• Neomycin Sulphate: An antibiotic that prevents bacterial infections by inhibiting protein synthesis in bacteria.
• Nystatin: An antifungal that disrupts fungal cell membranes, preventing fungal growth.

Therapeutic Class:

• Topical corticosteroids combined with antibiotics and antifungals.

Storage Conditions:
Store below 25°C and do not freeze. Keep in a dry place and out of reach of children.

FAQs

1. What conditions does Clovate N 15 Ointment treat?
   It treats severe inflammatory skin conditions like psoriasis, eczemas, and neurodermatitis, especially where secondary bacterial or fungal infections are present.
2. Can I use Clovate N 15 Ointment on my face?
   Use on the face is typically limited and should be done under medical supervision to avoid skin thinning and other side effects.
3. How long can I use Clovate N 15 Ointment?
   It is recommended for short-term use, up to 7 days without medical supervision, or up to 4 weeks under regular review by a healthcare provider.

Disclaimer

The provided information is for informational purposes only and not a substitute for professional medical advice. Always consult a healthcare professional for any medical conditions and treatment.

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