Generic

Generic Name: Cefixime Trihydrate
Ceftid-DS is an antibiotic that belongs to the third-generation cephalosporin group and is used primarily for bacterial infections sensitive to cefixime.

Description

Ceftid DS 50 ml Powder for Suspension, containing Cefixime Trihydrate at a concentration of 200mg/5ml, is an antibiotic medication produced by Opsonin Pharma Limited. It is prescribed for treating bacterial infections in adults and children, especially targeting respiratory tract infections, urinary tract infections, and certain sexually transmitted diseases.

Benefits

Ceftid DS provides effective treatment against infections caused by both gram-positive and gram-negative bacteria. It is particularly useful for treating respiratory tract infections, pharyngitis, tonsillitis, urinary tract infections, and uncomplicated gonorrhea. The stable formula withstands beta-lactamase enzymes, enhancing its effectiveness against bacteria resistant to other antibiotics.

Ingredients

Active Ingredient: Cefixime Trihydrate (200mg/5ml)
Inactive Ingredients: Powder base for suspension with flavoring and stabilizing agents.

Uses and Doses

Ceftid DS is used to treat infections like pharyngitis, tonsillitis, otitis media, bronchitis, and urinary tract infections.
Adults and Children over 12 years: 200-400 mg daily in a single or divided dose.
Children (6 months - 12 years): 8 mg/kg/day as a single or divided dose. For severe infections, dosing may extend up to 14 days. Dosage adjustments are needed in renal impairment cases.

Side Effects

Common side effects include diarrhea, nausea, abdominal discomfort, vomiting, headache, and dizziness. Occasionally, allergic reactions such as rash, urticaria, and itching may occur. More serious reactions are rare but may include blood abnormalities, hypersensitivity reactions, and gastrointestinal upset.

How to Use

Ceftid DS can be taken with or without food. Consistent dosing at the same time each day helps ensure effectiveness. Do not crush or chew the tablet; follow your physician’s instructions and complete the full course of treatment even if symptoms improve.

Pregnancy & Lactation

While no definitive studies confirm safety in pregnancy, Ceftid DS may be used if necessary under medical supervision. There is limited information on excretion into breast milk, so use cautiously during breastfeeding and consult a healthcare professional.

Precautions and Warnings

Avoid if you have a known allergy to cephalosporins. Patients with a history of gastrointestinal disorders, particularly colitis, should use this medication with caution. Adjust doses for those with severe renal impairment, and avoid unnecessary prolonged use to prevent antibiotic resistance.

Safety Information

Ceftid DS may raise prothrombin time when used with anticoagulants. Combining with carbamazepine can increase carbamazepine levels. Monitor kidney function in patients with renal impairment, and inform your healthcare provider of any history of allergies.

Indications

Ceftid DS treats a wide range of bacterial infections, including respiratory tract infections, otitis media, tonsillitis, pharyngitis, sinusitis, gonorrhea, and uncomplicated urinary tract infections.

Pharmacology

Cefixime is a third-generation cephalosporin antibiotic with broad-spectrum bactericidal properties. It interferes with cell wall synthesis by binding to penicillin-binding proteins (PBPs), essential for bacterial survival. Its stability against beta-lactamase enhances efficacy, especially in penicillin-resistant bacteria.

Therapeutic Class

Third-generation Cephalosporins

Storage Conditions

Store below 30°C, away from moisture and light. Keep out of children’s reach to prevent accidental ingestion.

3 FAQ

1. Can Ceftid DS treat viral infections?
   No, it is only effective against bacterial infections, not viral infections like the flu or common cold.
2. What should I do if I miss a dose?
   Take the missed dose as soon as you remember, but skip it if it’s almost time for your next dose. Avoid doubling doses.
3. Can Ceftid DS be used during pregnancy?
   Use only if absolutely necessary under medical supervision, as studies in pregnant women are limited.

Disclaimer

This information is provided as an overview and does not replace professional medical advice. Consult a healthcare provider for a personalized diagnosis and treatment plan.

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