Generic Canazole 50 contains Fluconazole, an antifungal medication used to treat various fungal infections.

Description: Canazole 50 is an antifungal medicine that works by inhibiting the growth of fungi. It is used to treat infections in the mouth, throat, vagina, nails, and other body parts. It destroys fungal cell membranes, preventing their spread and recurrence.

Benefits: Canazole 50 effectively treat various fungal infections, relieving symptoms such as itching, rashes, and discomfort. When used as prescribed, it prevents the recurrence of infection, provides targeted action against fungal cells, and is safe for most users under medical supervision.

Ingredients The active ingredient in Canazole 50 is Fluconazole. Other excipients may be present depending on the formulation.

Uses and Doses Canazole 50 treats fungal infections such as cryptococcal meningitis, candidiasis, tinea pedis, tinea cruris, and onychomycosis. The dosage depends on the condition being treated:

• Oropharyngeal candidiasis: 200 mg on the first day, then 100 mg daily for at least 2 weeks.
• Esophageal candidiasis: 200 mg on the first day, followed by 100 mg daily for at least 3 weeks.
• Vaginal candidiasis: Single dose of 150 mg.
• Systemic candidiasis: 400 mg on the first day, followed by 200-400 mg daily for 6-8 weeks.
• Pediatric dose: 3-12 mg/kg/day, depending on severity, with a maximum of 600 mg/day.
• Renal impairment: Adjusted based on creatinine clearance levels.

Side Effects Common side effects include headache, nausea, vomiting, abdominal pain, and rashes. In rare cases, severe reactions such as liver toxicity, QT prolongation, Stevens-Johnson syndrome, and anaphylaxis may occur.

How to Use: Take Canazole 50 as prescribed by your doctor. Swallow whole with or without food at the same time each day. Do not chew, crush, or break the tablet. If you miss a dose, take it as soon as possible, but skip it if the next dose is near. Avoid taking double doses.

Pregnancy & Lactation Canazole 50 should be avoided during pregnancy unless prescribed by a doctor for severe fungal infections. High doses during pregnancy have been associated with congenital disabilities. It is secreted in breast milk, so caution is advised while breastfeeding.

Precautions and Warnings: Patients with liver or kidney disorders should use Canazole 50 cautiously. It may prolong the QT interval, increasing the risk of cardiac arrhythmias. Avoid alcohol and consult your doctor before combining it with other medications.

Safety Information: Do not use Canazole 50 if you are allergic to Fluconazole. Inform your doctor of any underlying health conditions, including immune disorders, heart problems, or pregnancy. Prolonged use may require regular monitoring of liver function.

Indications Canazole 50 is indicated for fungal infections, including cryptococcal meningitis, candidiasis, onychomycosis, coccidioidomycosis, histoplasmosis, mucosal candidiasis, and dermatophytosis.

Pharmacology Fluconazole inhibits fungal ergosterol synthesis, disrupting fungal cell membranes and leading to cell death. It is highly effective against Candida, Cryptococcus, and other fungal species.

Therapeutic Class Antifungal agents.

Storage Conditions Store Canazole 50 at room temperature (15-30°C), away from moisture and direct sunlight. Keep out of reach of children.

3 FAQ

1. Can Canazole 50 be taken with food? Yes, it can be taken with or without food.
2. How long does Canazole 50 take to work? Symptoms usually improve within a few days, but the entire course must be completed.
3. Canazole 50 is safe for children, but dosage adjustments are required based on the child's weight and condition.

Disclaimer: This information is for educational purposes only. Consult your doctor for medical advice, diagnosis, or treatment.

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