Generic: The generic name of Cabolin 0.5 is Cabergoline, a dopamine receptor agonist used for treating conditions associated with high levels of prolactin, such as hyperprolactinemia caused by pituitary adenomas.

Description: Cabolin 0.5 is a prescription tablet containing 0.5 mg of Cabergoline. It is primarily used to manage disorders related to elevated prolactin levels in both men and women and also helps stop breast milk production after childbirth or in case of stillbirth. Manufactured by Renata Pharma Ltd, it is available in tablet form and must be used under medical supervision.

Benefits: Cabolin 0.5 helps regulate hormonal imbalance by reducing prolactin levels. It is beneficial in stopping lactation and treating hyperprolactinemic disorders. The drug also has a high affinity for D2 dopamine receptors, helping in conditions caused by excess prolactin secretion, especially when related to pituitary tumors.

Ingredients: Each Cabolin 0.5 tablet contains 0.5 mg of Cabergoline as the active ingredient.

Uses and Doses: Cabolin 0.5 is used to treat hyperprolactinemia, stop breast milk production, and address other hormonal conditions. The starting dose is 0.25 mg twice weekly, with gradual increments up to 1 mg, based on the patient’s serum prolactin level. Dosage adjustments should be made every 4 weeks, with periodic monitoring. To stop lactation, a 1 mg dose is recommended post-delivery. Doses for other conditions vary.

Side Effects: Patients using Cabolin 0.5 may experience side effects such as increased libido, hypersexuality, pathological gambling, and dizziness. These effects typically subside once the dosage is reduced or treatment is discontinued. Serious side effects include potential cardiovascular issues, for which regular heart check-ups are necessary.

How to Use: Cabolin 0.5 should be taken as directed by a healthcare provider, typically twice a week. It is essential to follow the prescribed dosage schedule, with adjustments made only by the doctor, and avoid taking the drug with blood pressure-lowering medications.

Pregnancy & Lactation: Cabolin 0.5 is classified under pregnancy category B. While no adequate human studies confirm harm, it should only be used during pregnancy if needed. It is unknown whether Cabergoline is excreted in human milk, so caution is advised for breastfeeding mothers.

Precautions and Warnings: Patients with cardiovascular conditions, severe liver disease, or mental illness should exercise caution when using Cabolin 0.5. Regular monitoring of prolactin levels and heart function is recommended, and the drug should not be taken with blood pressure-lowering medications.

Safety Information: Do not take Cabolin 0.5 if you have uncontrolled hypertension or a history of heart valve disorders. Be cautious of orthostatic hypotension, especially with higher doses. Store the medication in a cool, dry place away from children’s reach.

Indications: Cabolin 0.5 is indicated for the treatment of hyperprolactinemic disorders, cessation of lactation post-childbirth, and conditions caused by elevated prolactin levels, including pituitary adenomas.

Pharmacology: Cabergoline, the active ingredient in Cabolin 0.5, works as a long-acting dopamine receptor agonist. It specifically inhibits prolactin secretion from the pituitary gland by binding to dopamine D2 receptors.

Therapeutic Class: Cabolin 0.5 belongs to the antiparkinson drugs class, used for its dopamine receptor agonist effects.

Storage Conditions: Store Cabolin 0.5 tablets in a cool, dry place below 30°C, away from moisture and light. Keep out of children's reach.

FAQ:

1. How long should Cabolin 0.5 be taken?
   Duration depends on the condition and doctor's recommendation, with periodic monitoring.
2. Can Cabolin 0.5 stop lactation completely?
   Yes, it helps stop milk production after childbirth or in cases of stillbirth.
3. Is Cabolin 0.5 safe during pregnancy?
   It is a pregnancy category B drug, meaning it should only be used if necessary.

Disclaimer: This information is not intended to replace medical advice. Always consult a healthcare professional before using Cabolin 0.5 or adjusting its dosage.

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