Generic
Bisoren M 2.5 Tablet combines bisoprolol fumarate (2.5mg) and Amlodipine Besilate (5mg), which are used primarily to treat hypertension.

Description
Bisoren M 2.5 Tablet combines a cardio-selective β-blocker (Bisoprolol) and a vasoselective calcium channel blocker (Amlodipine). Together, they reduce blood pressure and prevent complications such as heart attack and stroke.

Benefits
This combination effectively lowers blood pressure by decreasing cardiac output and relaxing blood vessels, reducing the strain on the heart. It helps prevent hypertension-related complications, including cardiovascular diseases.

Ingredients
The active ingredients are bisoprolol Fumarate (2.5mg) and amlodipine Besilate (5mg). Pharmaceutical standards require stabilizers and fillers as excipients.

Uses and Doses
Indicated for treating mild to moderate hypertension in adults. The recommended dosage is one tablet daily, taken with or without food, preferably at the same time each day.

Side Effects
Common side effects include headache, dizziness, slow heart rate, nausea, fatigue, ankle swelling, and flushing. Rarely, it may cause cold extremities, sleep disturbances, or postural hypotension.

How to Use
Swallow one tablet whole daily without crushing or chewing. Consistent timing ensures optimal efficacy. Do not discontinue use abruptly without consulting a physician.

Pregnancy & Lactation
It is not recommended during pregnancy unless it is essential. Insufficient data exists on its safety during breastfeeding; consult a doctor before using it in nursing mothers.

Precautions and Warnings
Avoid use in patients with acute heart failure, cardiogenic shock, severe aortic stenosis, or hypersensitivity to the components. Caution is advised in diabetes, hepatic impairment, or bronchospastic diseases.

Safety Information
Monitor blood pressure and heart rate regularly during treatment. Avoid combining with other medications that may cause hypotension or bradycardia without medical advice.

Indications
Primarily indicated for hypertension treatment in patients controlled by the individual components given concurrently in the same dosage levels as in the combination.

Pharmacology
Bisoprolol reduces cardiac output by β1-selective blockade, while Amlodipine relaxes vascular smooth muscle by inhibiting calcium ion influx, lowering peripheral resistance, and improving myocardial oxygen delivery.

Therapeutic Class
Antihypertensive medications are a combination of a β-blocker and a calcium channel blocker.

Storage Conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.

3 FAQ

1. Can Bisoren M 2.5 Tablet cause dizziness?
   Yes, dizziness is a common side effect, especially at the start of therapy. Rise slowly from sitting or lying positions.
2. Is it safe to stop Bisoren M suddenly?
   No, abrupt discontinuation may lead to rebound hypertension or heart complications. Consult your doctor before stopping.
3. Can I take Bisoren M during pregnancy?
   It is not recommended during pregnancy unless necessary, as safety data is limited.

Disclaimer
Always consult your doctor before starting or stopping the Bisoren M 2.5 Tablet. This information is not a substitute for professional medical advice.

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