Generic

Trimetazidine Dihydrochloride

Description

Angimet MR is an anti-ischemic and anti-anginal medication containing Trimetazidine Dihydrochloride 35 mg, manufactured by Orion Pharma Ltd. It is used as an add-on therapy for stable angina pectoris, helping patients who do not respond well to first-line anti-anginal treatments. It enhances cardiac energy efficiency, reducing the frequency and severity of angina attacks.

Benefits

Angimet MR improves cardiac metabolism, ensuring better oxygen utilization in the heart muscles. This leads to enhanced energy production, reduced lactic acid accumulation, and improved heart function. It also helps prevent ischemic damage, making it beneficial for patients suffering from chronic angina and heart failure.

Ingredients

Each tablet contains 35 mg of trimetazidine dihydrochloride, optimizing cardiac energy metabolism by shifting the heart’s energy source from fatty acid to glucose oxidation. This improves the heart's energy efficiency.

Uses and Doses

Angimet MR is prescribed for stable angina pectoris as an add-on treatment for patients unresponsive to other anti-anginal drugs.

• Recommended Dose: 35 mg twice daily or 20 mg three times daily with meals.
• Treatment Assessment: If there is no response after three months, the medication should be discontinued.

Side Effects

Angimet MR is generally well-tolerated, but some patients may experience dizziness, headache, stomach discomfort, nausea, vomiting, diarrhea, skin rash, itching, or fatigue.

How to Use

Take one tablet twice daily or as directed by your doctor. Swallow the tablet whole with water, preferably with meals, to enhance absorption and minimize gastrointestinal discomfort.

Pregnancy & Lactation

There is no sufficient data on the use of Trimetazidine during pregnancy. Animal studies indicate no direct harm, but it is recommended to avoid use during pregnancy as a precaution. It is not known whether the drug passes into breast milk, so breastfeeding mothers should avoid using it.

Precautions and Warnings

Angimet MR is not a first-line treatment for angina attacks or myocardial infarction. It should not be used as a standalone therapy for heart conditions. Patients with Parkinson’s disease, tremors, or restless leg syndrome should avoid this medication.

Safety Information

This medication does not interact with other anti-anginal or heart-related drugs, making it safe to use alongside beta-blockers, calcium channel blockers, nitrates, and heparin. However, it is not a substitute for acute angina treatment and should not be used for emergency cardiac conditions.

Indications

Angimet MR is indicated for stable angina pectoris in patients who require additional treatment to manage symptoms when first-line medications do not provide sufficient relief.

Pharmacology

Trimetazidine is a 3-ketoacyl CoA thiolase inhibitor that shifts energy production in the heart from fatty acid metabolism to glucose metabolism. This allows the heart to use oxygen more efficiently, reducing ischemic damage, preventing lactic acid buildup, and enhancing overall cardiac performance.

Therapeutic Class

Other Anti-anginal & Anti-ischemic drugs

Storage Conditions

Store in a dry place away from light and heat. Keep out of children’s reach.

3 FAQ

Q1: Can Angimet MR be used alone for angina treatment?
No, it is only used as an add-on therapy when first-line anti-anginal drugs are not effective.

Q2: Does Angimet MR cause drowsiness?
No, but some patients may experience dizziness or fatigue, so caution is advised when driving or operating machinery.

Q3: How long does it take for Angimet MR to show results?
It varies by patient, but improvements are usually seen within a few weeks of regular use.

Disclaimer

This information is for educational purposes only and should not replace medical advice. Always consult a healthcare professional before using this medication.

 

 

 

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