Generic:
Anaflex Max 500 is a combination medication consisting of Esomeprazole 20mg and Naproxen Sodium 500mg. It is manufactured by ACI Limited and offers an effective treatment for conditions involving inflammation and pain relief, while also protecting against NSAID-associated stomach ulcers.

Description:
Anaflex Max 500 is a dual-action medication designed to treat pain and inflammation associated with arthritis and prevent stomach irritation caused by NSAIDs. The combination of Naproxen and Esomeprazole targets both the pain relief and gastric protection needs of patients, making it an ideal solution for those requiring long-term NSAID treatment.

Benefits:
Anaflex Max 500 is highly effective in reducing pain, inflammation, and symptoms of arthritis, such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Additionally, it helps prevent the development of gastric ulcers in patients at risk of NSAID-induced stomach problems, providing both therapeutic and protective benefits.

Ingredients:
Anaflex Max 500 contains two key ingredients:

• Esomeprazole 20mg: A proton pump inhibitor that reduces stomach acid secretion.
• Naproxen Sodium 500mg: A nonsteroidal anti-inflammatory drug (NSAID) that alleviates pain and inflammation.

Uses and Doses:
Anaflex Max 500 is used to treat osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and reduce the risk of NSAID-related gastric ulcers. The typical dosage for adults and adolescents is one tablet twice daily, with options for 375 mg Naproxen/20 mg Esomeprazole or 500 mg Naproxen/20 mg Esomeprazole, depending on the patient's condition and weight.

Side Effects:
Anaflex Max 500 is generally well tolerated. However, common side effects may include erosive gastritis, dyspepsia, gastritis, diarrhea, upper abdominal pain, nausea, and gastric ulcers. These side effects are typically mild and temporary but should be monitored.

How to Use:
For adults and adolescents over 12 years, Anaflex Max 500 should be taken twice daily, with or without food, based on the prescribed dose. It is crucial to follow the prescribed dosage and use the medication for the shortest duration necessary to manage symptoms.

Pregnancy & Lactation:
Anaflex Max 500 falls under pregnancy category C. It should be avoided during late pregnancy due to the risk of premature closure of the ductus arteriosus. The medication is contraindicated for nursing mothers due to the Naproxen component, which can be excreted in breast milk.

Precautions and Warnings:
Anaflex Max 500 should be used with caution in patients with cardiovascular disease or risk factors, fluid retention, or heart failure. Patients should also be monitored for gastrointestinal issues, especially when using the medication long-term.

Safety Information:
Anaflex Max 500 should not be used in patients with hypersensitivity to its components or those who have experienced allergic reactions to NSAIDs, such as asthma or urticaria. It is contraindicated in patients undergoing coronary artery bypass graft (CABG) surgery.

Indications:
Anaflex Max 500 is indicated for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and the prevention of NSAID-associated gastric ulcers in patients at risk.

Pharmacology:
Naproxen works by inhibiting the production of prostaglandins, which are chemicals in the body involved in pain and inflammation. Esomeprazole works by inhibiting the proton pump in the stomach, reducing acid secretion, and helping to protect the stomach lining from irritation caused by NSAIDs.

Therapeutic Class:
Anaflex Max 500 belongs to the therapeutic class of drugs for osteoarthritis, rheumatoid arthritis, and NSAIDs, providing both analgesic and gastrointestinal protective effects.

Storage Conditions:
Store Anaflex Max 500 below 30°C, away from light and moisture, and keep it out of reach of children to ensure its safety and efficacy.

3 FAQ:

1. What are the primary uses of Anaflex Max 500?
   Anaflex Max 500 is used to treat arthritis, including osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and to prevent gastric ulcers in patients using NSAIDs.
2. Can I take Anaflex Max 500 with food?
   Yes, Anaflex Max 500 can be taken with or without food, but taking it with a high-fat meal may reduce its peak plasma concentration.
3. Are there any side effects to Anaflex Max 500?
   Common side effects include gastric irritation, upper abdominal pain, nausea, and diarrhea. These are typically mild but should be monitored.

Disclaimer:
This information is not a substitute for professional medical advice. Consult a healthcare provider before using Anaflex Max 500 to ensure its safety and efficacy in your specific case.