Generic

Prazosin Hydrochloride

Description

Alphapress XR 2.5 is an extended-release tablet containing Prazosin Hydrochloride 2.5 mg, manufactured by Renata Pharma Ltd. It is primarily prescribed for hypertension, Raynaud's phenomenon, congestive heart failure, and benign prostatic hyperplasia.

Benefits

Alphapress XR 2.5 offers effective control of blood pressure in hypertensive patients, improves cardiac output in congestive heart failure, and alleviates urinary symptoms in benign prostatic hyperplasia. Additionally, it reduces symptoms of Raynaud's disease.

Ingredients

The main active ingredient in Alphapress XR 2.5 is Prazosin Hydrochloride, 2.5 mg per tablet.

Uses and Doses

For hypertension, the recommended starting dose is 0.5 mg twice or thrice daily, gradually increasing to a maintenance dose based on the patient's response. In congestive heart failure, the usual maintenance dosage ranges from 4 mg to 20 mg in divided doses. For Raynaud’s disease, the starting dose is 0.5 mg twice daily. In benign prostatic hyperplasia, the initial dose is 0.5 mg twice daily, adjusted based on clinical response.

Side Effects

Common side effects include dizziness, drowsiness, headache, faintness, blurred vision, palpitations, and occasional postural hypotension. Serious side effects may include allergic reactions, hallucinations, and worsening of pre-existing narcolepsy.

How to Use

Alphapress XR 2.5 may be taken with or without food, preferably in the evening, 2-3 hours before bedtime for the starting dose. Maintenance doses can be taken at any time of the day with or without food.

Pregnancy & Lactation

Alphapress XR 2.5 is classified as a Pregnancy Category C drug, meaning it should be used only when the potential benefits outweigh the risks. It is excreted in small amounts in breast milk, so caution is advised for nursing mothers.

Precautions and Warnings

Patients with a history of micturition syncope or postural hypotension should be cautious. Alphapress is not recommended for congestive heart failure caused by mechanical obstruction. It should also be avoided in combination with other alpha-1 blockers.

Safety Information

Use caution in patients with pre-existing hypotension, syncope, or heart valve conditions. Careful monitoring is required in elderly patients or those starting concurrent antihypertensive therapy.

Indications

Alphapress XR 2.5 is indicated for the treatment of hypertension, Raynaud’s disease, congestive heart failure, and benign prostatic hyperplasia.

Pharmacology

Prazosin Hydrochloride works by selectively inhibiting alpha-1-adrenoreceptors, reducing peripheral vascular resistance, and lowering blood pressure without causing reflex tachycardia. It enhances cardiac output in heart failure patients and improves urinary symptoms in benign prostatic hyperplasia.

Therapeutic Class

Alpha-adrenoceptor blocking drugs

Storage Conditions

Store Alphapress XR 2.5 tablets below 30°C, away from light and moisture. Keep out of reach of children.

3 FAQ

1. What is Alphapress XR 2.5 used for?
   Alphapress XR 2.5 is used to treat hypertension, Raynaud’s disease, congestive heart failure, and benign prostatic hyperplasia.
2. Can Alphapress XR 2.5 cause dizziness?
   Yes, dizziness and faintness may occur, particularly during the first dose or when increasing the dosage.
3. Is Alphapress XR 2.5 safe during pregnancy?
   Alphapress XR 2.5 is classified as Pregnancy Category C and should only be used if the potential benefits outweigh the risks.

Disclaimer

Consult a healthcare provider for medical advice regarding any treatment, dosage adjustments, or side effects. This summary is for informational purposes only and does not replace professional medical advice.

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