Generic

The generic name of Adarbi 40 is Azilsartan Medoxomil, which belongs to the class of angiotensin II receptor blockers (ARBs). It is primarily prescribed for managing hypertension and reducing cardiovascular risks in patients.

Description

Adarbi 40, containing Azilsartan Medoxomil at a dose of 40 mg, is used to treat high blood pressure. It is available in tablet form and is produced by Nipro JMI Pharma Ltd. This antihypertensive medication works effectively by relaxing blood vessels, thereby improving blood flow and reducing cardiovascular strain.

Benefits

Adarbi 40 offers significant cardiovascular benefits by effectively reducing high blood pressure, lowering the risk of heart attack and stroke, and supporting heart and kidney health. For diabetic patients, it helps preserve kidney function, especially when administered long-term and under regular medical supervision.

Ingredients

Each Adarbi 40 tablet contains 40 mg of Azilsartan Medoxomil as the active ingredient. Inactive components used to bind the tablet and support its efficacy may include other pharmacologically inert ingredients.

Uses and Doses

Adarbi 40 is used for treating high blood pressure and preventing cardiovascular complications such as heart attacks and strokes. The recommended starting dose for adults is 40 mg taken orally once daily, with a maximum dose of 80 mg per day if necessary. Patients on high doses of diuretics are usually advised to start with a lower dose of 40 mg.

Side Effects

Common side effects of Adarbi 40 include dizziness, muscle spasms, diarrhea, and fatigue. Less commonly, some patients may experience nausea, hypotension, or respiratory issues. Severe side effects are rare, but users should consult a doctor if they experience persistent adverse symptoms.

How to Use

Adarbi 40 tablets should be swallowed whole with or without food, ideally taken at the same time each day. It should not be crushed or chewed. Patients should follow their doctor’s dosage instructions and avoid doubling the dose in case of a missed dose.

Pregnancy & Lactation

Azilsartan Medoxomil is classified as Pregnancy Category D, which indicates potential risks to the fetus, especially during the second and third trimesters. While it is unclear if it is excreted in human milk, caution is advised. Nursing mothers should consider alternative treatments or cease breastfeeding while on Adarbi 40.

Precautions and Warnings

Patients with a history of renal or liver impairment should exercise caution with Adarbi 40, as it may lead to renal complications, particularly if they are taking potassium supplements or NSAIDs. Blood pressure and kidney function monitoring are recommended for long-term use.

Safety Information

Patients taking Adarbi 40 should avoid activities requiring full alertness if dizziness occurs. Caution is advised when combining this drug with potassium-sparing diuretics or supplements to prevent hyperkalemia. NSAID usage should be minimized to avoid reduced efficacy and potential kidney risks.

Indications

Adarbi 40 is indicated for the treatment of hypertension, helping to reduce cardiovascular risks such as myocardial infarction and stroke. It may be prescribed as a monotherapy or in combination with other antihypertensive agents to optimize blood pressure control.

Pharmacology

Azilsartan Medoxomil is a prodrug hydrolyzed to Azilsartan during gastrointestinal absorption. It selectively inhibits the AT1 angiotensin II receptor, reducing vasoconstriction and aldosterone secretion, ultimately lowering blood pressure and improving blood flow.

Therapeutic Class

Adarbi 40 belongs to the Angiotensin II receptor blocker (ARB) class, specifically targeting blood pressure regulation by blocking specific receptors that contribute to vascular constriction.

Storage Conditions

Adarbi 40 should be stored in a cool, dry place, away from direct light and moisture, and kept out of reach of children. It is best stored at temperatures below 30°C.

3 FAQ

1. Can Adarbi 40 be taken with other medications?
   Adarbi 40 can be combined with other antihypertensive medications as prescribed, but certain NSAIDs and potassium supplements should be avoided to prevent interactions.
2. What should I do if I miss a dose of Adarbi 40?
   If you miss a dose, skip it and continue with your normal schedule. Avoid taking a double dose.
3. Is Adarbi 40 safe during pregnancy?
   Adarbi 40 is generally not recommended during pregnancy due to fetal risk, particularly in the second and third trimesters

   Disclaimer

   This information is for educational purposes and is not a substitute for medical advice. Patients should consult their healthcare provider regarding any concerns or for personalized treatment recommendations before starting or stopping Adarbi 40.

   Keywords: Adarbi 40, Azilsartan Medoxomil, high blood pressure, hypertension treatment, angiotensin II receptor blocker, ARB, Nipro JMI Pharma, cardiovascular health, blood pressure control, antihypertensive medication, kidney protection, heart disease prevention, side effects, dosing information, pregnancy safety, drug interactions, how to use, precautions, storage instructions, therapeutic class.

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