Generic

Abetis Plus 40 Tablet contains Olmesartan Medoxomil 40mg and Hydrochlorothiazide 12.50mg, manufactured by ACI Limited.

Description

Abetis Plus 40 is used to treat hypertension. It combines Olmesartan Medoxomil, an angiotensin II receptor antagonist, and Hydrochlorothiazide, a thiazide diuretic, to control blood pressure effectively when Olmesartan alone is insufficient.

Benefits

• Effective control of hypertension
• Reduces the risk of heart attacks and strokes
• Combination therapy improves blood pressure control
• Helps maintain kidney function

Ingredients

• Olmesartan Medoxomil 40mg
• Hydrochlorothiazide 12.50mg

Uses and Doses

Abetis Plus 40 is indicated for hypertension treatment in patients not adequately controlled on Olmesartan alone. The typical starting dose is one tablet of Abetis Plus 20/12.5 once daily, which may be increased to two tablets of Abetis Plus 40/25 daily based on blood pressure response.

Side Effects

Common side effects include nausea, headache, dizziness, diarrhea, and electrolyte imbalance. Severe side effects like acute renal failure are rare but possible.

How to Use

Take Abetis Plus 40 as prescribed by your doctor, with or without food, preferably in the morning. Swallow the tablet whole without crushing or chewing.

Pregnancy & Lactation

Abetis Plus 40 is not recommended during pregnancy, especially in the second and third trimesters (Pregnancy Category D). It is unknown if Olmesartan is excreted in human milk, but Hydrochlorothiazide appears in breast milk. A decision must be made to either discontinue nursing or the medication.

Precautions and Warnings

Monitor for signs of fluid or electrolyte imbalance. Not recommended for patients with severe renal impairment. Use caution in patients with renal artery stenosis and those who are volume- or salt-depleted.

Safety Information

Keep out of reach of children. Store in a cool, dry place away from light and moisture. Regular monitoring of kidney function and electrolytes is essential during therapy.

Indications

Abetis Plus 40 is indicated for the treatment of hypertension in patients not adequately controlled on Olmesartan alone. It is not for initial therapy.

Pharmacology

Olmesartan Medoxomil blocks the effects of angiotensin II on the AT1 receptor in vascular smooth muscle, reducing vasoconstriction. Hydrochlorothiazide increases the excretion of sodium and chloride, reducing plasma volume and subsequently lowering blood pressure.

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Store in a cool, dry place, protected from light and moisture. Keep out of reach of children.

3 FAQ

1. What is Abetis Plus 40 used for? Abetis Plus 40 is used to treat hypertension when Olmesartan alone is insufficient.
2. Can Abetis Plus 40 be taken during pregnancy? Abetis Plus 40 is not recommended during pregnancy, especially in the second and third trimesters.
3. What are the common side effects of Abetis Plus 40? Common side effects include nausea, headache, dizziness, diarrhea, and electrolyte imbalance.

Disclaimer

The information provided is for informational purposes only and is not a substitute for professional medical advice. Always seek the advice of a physician with any questions regarding a medical condition.

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