Generic

Ferric Carboxymaltose

Description

Ferisen-IV 1/20 ml Injection, manufactured by Healthcare Pharmaceuticals Limited, contains Ferric Carboxymaltose, which is an intravenous form of iron. It is designed to treat iron deficiency anemia, especially in patients who cannot tolerate oral iron or have chronic kidney disease. This injection helps replenish iron levels in the body, promoting proper oxygen transport and energy production.

Benefits

Ferisen-IV aids in treating iron deficiency anemia in adults who are unable to use oral iron. It helps increase hemoglobin levels, restores iron reserves, and boosts overall energy. Suitable for patients with chronic kidney disease or those intolerant to oral supplements, it provides fast, effective iron replenishment.

Ingredients

Ferric Carboxymaltose 50 mg of elemental iron per mL in a 20 mL vial.

Uses and Doses

• For patients weighing 50 kg or more: Administer two doses of 750 mg, separated by at least 7 days, for a cumulative total of 1500 mg of iron per course.
• For patients under 50 kg: Administer 15 mg/kg per dose, with a total cumulative dose not exceeding 1500 mg of iron per course.
• Administer intravenously, either via slow push or infusion.

Side Effects

Common side effects include nausea, hypertension, dizziness, vomiting, and low blood phosphorus levels. Some patients may experience injection site discoloration, headaches, or allergic reactions like pruritus, rash, or anaphylactic responses.

How to Use

Administer Ferisen-IV as an intravenous injection, either undiluted through a slow push or diluted in 0.9% sodium chloride solution for infusion. When diluted, ensure that the solution has an iron concentration of 2-4 mg per mL and administer over at least 15 minutes.

Pregnancy & Lactation

Classified as Pregnancy Type C, Ferisen-IV may have harmful effects on the fetus according to animal studies. While there are no well-controlled human studies, potential benefits may warrant use in pregnant women despite possible risks.

Precautions and Warnings

Severe hypersensitivity reactions, including life-threatening anaphylactic reactions, may occur. Monitor patients for at least 30 minutes after infusion. Be cautious with patients showing signs of hypertension, and avoid extravasation, which may cause long-lasting brown discoloration at the injection site.

Safety Information

Ensure that patients are stable and monitored for adverse reactions after administration. Avoid use in patients with known hypersensitivity to any of its constituents.

Indications

Ferisen-IV is indicated for the treatment of iron deficiency anemia in adults intolerant to oral iron or those with chronic kidney disease.

Pharmacology

Ferric carboxymaltose is a colloidal iron hydroxide complex bound to a carbohydrate polymer. It releases iron to replenish body iron reserves, aiding oxygen transport via hemoglobin.

Therapeutic Class

Parenteral Iron Preparations

Storage Conditions

Store at temperatures no higher than 30°C. Keep out of the reach of children and do not freeze.

3 FAQ

1. What is Ferric Carboxymaltose used for?
   It is used to treat iron deficiency anemia in patients who cannot tolerate oral iron or have chronic kidney disease.
2. How is it administered?
   It is given intravenously, either undiluted or diluted with sodium chloride solution.
3. Are there any side effects?
   Common side effects include nausea, hypertension, dizziness, and allergic reactions.

Disclaimer

The information provided is for educational purposes and is not intended as medical advice. Always consult with a healthcare provider for personalized recommendations and treatment plans.

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